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Neuropathic pain Neuropathic pain is a chronic painful condition caused by damage to the nervous system, often resulting in allodynia and hyperalgesia, which are difficult to treat with conventional medications

Therefore, in exploring the regulation of redox states for disease treatment, precise targeting of specific DNA repair enzymes can be considered

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Mammals usually rely solely on extracellular uptake as the primary source of Cys, but some mammals also use cystathionine -lyase (CGL)-mediated cystathionine-cleavage in the transsulfuration pathway as a surrogate Cys source if System X c is blocked (Shimada and Stockwell, 2016)