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Description

These enzymes convert acetyl-CoA into malonyl-CoA and further into palmitic acid, the SFA, which can be desaturated into MUFAs by stearoyl-CoA desaturase 1 (SCD1) (44, 45)

In this study, we expanded our screening efforts to a library of ~ 320,000 small molecules to identify chemical scaffolds that inhibit p6*-PR precursor autoprocessing