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Use dose changes thoughtfully: Sometimes the answer is time

In the present study, we carried forward these four ACs and tested whether the relationships with depression predicted from genomic data (negative with C2 and C3, and positive with C8 and C10) were expressed in actual phenotypes measured in a large cohort (N ~ 2500) with extensive clinical phenotyping

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In combination, the IC 50 value is reached at concentrations of EA and cryptotanshinone of 3.3 M and 0.68 M, respectively, similar to the MCF-7 cell line showing that combining competitive and non-competitive GST P1-1 inhibitors is optimal