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doi: 10.1084/jem.20151750 42 OhneYSilverJSThompson-SnipesLColletMABlanckJPCantarelBLet al

While nucleophilic trapping studies and covalent protein binding assays adequately assess the bioactivation potential of a drug (Evans et al

Curcumin is a natural polyphenol that shows great potential for use in the treatment of human diseases

Lipid mediators (such as SAPE-OOH) and DAMPs such as HMGB1 and ATP released from ferroptotic cells can be used as find me and eat me specific signals to activate the macrophage immune response through pattern recognition receptors (PRRs) (184)