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H.ZhouY.SchroederS.HaroutunianV.SeeleyW

20 Astrocytic reactivity is highly context dependent and is manifested by many different reactive phenotypes or transient states

People at Risk The risk of adverse effects is especially high in people with [70+]: Digestive conditions (Crohns disease, ulcerative colitis, diverticulitis) A history of bowel surgery Severe hemorrhoids Kidney, heart, and liver disease Allergy to coffee The FDA only approves colon cleansing to prepare for medical procedures and has issued several letters warning about unapproved uses

BD COs showed increased ROS, ccf-mtDNA, and dsDNA, thus, these findings provide a comprehensive view of the extent of dysregulated cellular homeostasis in BD COs [15]