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Cellular and Molecular Immunology (Review)

To this end, we added catalase (CAT, EC Number: 1.11.1.6), a key antioxidant enzyme that protects the cells from H 2 O 2 -mediated cellular damage by converting the H 2 O 2 to water and oxygen [21]

Similarly, it is also known that GPx7 -deficient cells accumulate endogenous ROS, lowering cellular viability 8,10 , and especially in breast cancer cells, GPX7 is essential for reducing the oxidative stress generated by specific polyunsaturated fatty acids 112