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Regular blood tests help catch any deficiencies early Spirulina does not contain (useful) B12 Spirulina was once thought to be a source of B12, but unfortunately it actually contains a B12 analogue - an "inactive" B12 that competes with active B12 for absorption, so it may actually speed up a deficiency

Adderall and dextroamphetamine give users the feeling of more energy, and students misuse the drugs to help stay awake for long periods, particularly in exam season when they might want to stay up late studying

Patients with food-bound cobalamin malabsorption (FBCM) may need to take cobalamin supplements on an empty stomach

A few small studies and case reports have not flagged major safety concerns