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doi:10.1080/09513590.2020.1810657 Lagana AS, Vitagliano A, Noventa M, Ambrosini G, D'Anna R

This lactate subsequently induces histone or nonhistone lactylation, playing a pivotal role in the progression of IRI

HNO donors induce vasodilation and contribute to the prevention of atherosclerosis and vascular thrombosis, and HNO is a promising alternative clinical cardiac inotropic agent in heart failure 33,34,35,36,37,38,39,40,41