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Captured anti-PEG antibodies were colorimetrically detected using a rabbit anti-human IgG and IgM antibody conjugated to HRP (Jackson ImmunoResearch, #309-035-107) and TMB substrate

94 The role of ATM as a sensor of oxidative stress suggests a novel function independent of DNA damage repair that is crucial for preventing DNA damage under oxidative stress conditions

There is no doubt that oxidative damage, in the form of protein carbonyl formation, was discovered in the midbrain, olfactory bulb, striatum, and cortex of rats that were treated with rotenone [95]

With existing clinical data on Polmacoxib limited to only two previous studies, this prospective, multicenter, open-label observational study contributes meaningful real-world insights by examining its effectiveness, onset of action, and safety and tolerability over an eight-week period in everyday Indian clinical practice