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doi: 10.1016/j.apjtb.2016.09.006

While glutathione has a number of benefits for overall health and wellness, it can be particularly helpful in supporting liver health and function in dogs and cats

Interestingly, gene inhibition and CB-839, an inhibitor of GLS activity, can eliminate SREBP activation, suggesting that ammonia derived from GLS is a critical mediator of lipogenesis (90, 142)

Their capacity to regulate drug resistance proteins, metabolic pathways, and immune cell phenotypes renders them promising candidates for combination therapies aimed at overcoming MDR and improving the outcomes of cancer treatment