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There is evidence that combining caffeine and some antidepressants may affect Glu, adenosine and monoamine systems associated with depression, perhaps in an additive manner to reverse depressive pathophysiology [266]

GSH-conjugated UV filters increase with a corresponding decrease in free GSH, and therefore may contribute to a decreased capacity for nuclear GSH to protect lens proteins from cross-linking and insolubilisation (110)

As a control, some cells were also given 100 U/mL catalase just prior to exposure to hydrogen peroxide

By dismantling HO and peroxides, GPx shields lipids, proteins, and DNA from oxidation, averting mutations or breakdowns