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Cavallini et al

A new GLS1 inhibitor compound 27 (IPN60090) was developed by replacing the flexible core of CB-839 with heterocycles

doi: 10.3389/fgene.2020.00095 Received 05 November 2019 Accepted 28 January 2020 Published 28 February 2020 Volume 11 - 2020 Edited by Nejat Dalay, Istanbul University, Turkey Reviewed by Girdhari Lal, National Centre for Cell Science, India

As stated above [37], a reduction in muscle AR levels has been detected during age-related muscle loss [75] and a decrease in AR protein levels has been reported in skeletal muscle biopsies from older compared to young people [76]