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Description

The starting conformations were obtained by manually binding GS(H) to a snapshot of the MD simulation of TRaQ-G and the crystal structure of MeTRaQ-G, respectively

(Zinc Gluconate):

Nevertheless, the increase of PyroGlu and decrease of Glu seems more reflecting the low ATP cellular content leading to a locking of the gamma-glutamyl cycle from the first step requiring ATP after PyroGlu synthesis

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