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established the feasibility of RNA expression analysis of samples obtained by EBUS TBNA with microarrays ( Kim et al

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however, each method has certain drawbacks [111,112,113,114,115]

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Delgado-Peraza et al further reinforce this connection by demonstrating a strong predictive relationship between MP loads in EVs derived from both neurons and astrocytes, and brain pathology in mouse models of Alzheimers disease

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In both cases, large regions of disorder can have a negative impact on the prediction of nearby folds as discussed in the previous section

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