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The limited human data available has not shown significant safety concerns, but long-term human safety data is still being established

Managing Lower Back Pain with Epidural Spinal Injections Spinal injections use powerful corticosteroid medications to reduce pain

Cancer Cell 18 , 655668 (2010)

As a pro-inflammatory cytokine, the expression of TGF-b undergoes down-regulation in rat exposed to curcumin (200 mg/kg), leading to amelioration of inflammation (Wang et al., 2019a)