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Description

Pinch a layer of skin with your thumb and index finger, which should be about an inch and a half apart from each other, in the front area of the thigh

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Compound: 5-Amino-1-methylquinolinium iodide (5-Amino-1MQ)

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Cell-culture (3T3-L1 adipocytes) 5-Amino-1MQ at 30 M strongly reduced 1-MNA levels in mouse fat cells, confirming NNMT inhibition (Neelakantan et al., Biochemical Pharmacology, 2018)

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UK-wide licensing for human medicines

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