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Osteopontin and CD44, markers of the HFSC niche, were also increased

Current scientific evidence includes extensive animal studies, which demonstrate enhanced tendon, ligament, and muscle repair, improved angiogenesis, and anti-inflammatory effects, providing mechanistic insight into its regenerative potential

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This model of MRP1, built long before the release of the Cryo-EM structure of human MRP1 40 , remains in adequacy with the published Cryo-EM structure, validating our choice of mutants