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We treated TC1-6 cells with serum collected from WT or GCGR-KO mice for 72 h and found that VGF and proglucagon protein levels were significantly increased in GCGR-KO serum-treated cells (Fig

Un estudio in vitro de 2025 reprodujo el alargamiento telomrico en fibroblastos y clulas epiteliales normales por la va hTERT/telomerasa, y report que en lneas de clulas cancerosas la extensin telomrica ocurri en cambio a travs del mecanismo de Alargamiento Alternativo de Telmeros (ALT) , pese a la regulacin al alza de hTERT (PMID 40908429)