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There are several different dosing regimens for this type of B12 therapy

Geisler et al

[DOI] [PubMed] [Google Scholar] 387.Xiao M., Wang T., Zhu T., Wen F

In one study, PPC prevented alcohol-induced depletion of liver S-Adenosyl Methionine (SAMe), which was associated with preservation of liver glutathione levels in rats (Aleynik 2003)