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Methods Ethics statement All animal-based experiments were performed using the protocol (M005916-R01-A01) approved by the Animal Use and Care Committee of the University of WisconsinMadison and consistent with the standards of the National Institutes of Health

*Correspondence: Xi Cheng, [email protected] Niu, [email protected] These authors have contributed equally to this work and share first authorship This article was submitted to Dementia and Neurodegenerative Diseases, a section of the journal Frontiers in Neurology Disclaimer All claims expressed in this article are solely those of the authors and do not necessarily represent those of their affiliated organizations, or those of the publisher, the editors and the reviewers

doi: 10.1001/archpsyc.62.6.593 [DOI] [PubMed] [Google Scholar] 7.Koran LM, Abujaoude E, Large MD, Serpe RT

H., Posey, D