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It is worth noting that Fig.3 highlights four major issues affecting the effectiveness and safety of Se-based treatments: (1) a narrow therapeutic window requiring precise dosing to avoid toxicity or ineffectiveness

However, hypomania/mania switch has also been reported with creatine monohydrate supplementation [65, 66], highlighting that targeting only mitochondrial function may not be sufficient to treat bipolar depression

Monitoring blood glucose levels and working closely with your healthcare provider is essential if you have diabetes and wish to use glutathione supplements

Paper presented at the IOP Conference Series: Materials Science and Engineering