However, the accumulation of ferric ion and ferrous ions was observed in the ovarian tissues of breast cancer model mice with POI, suggesting that CTX-induced POI could be significantly improved upon supplementation with serine (Fig
6 It can also lead to esophageal reflux, stomach upset, and frequent need to urinate, all of which can cause frequent awakenings and difficulty falling asleep, as well as possible injury from unsteadiness during trips to the bathroom
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The ketone bodies cross the blood-brain barrier and are used instead of glucose, thereby sparing glucose for use in other metabolic pathways, such as the pentose-phosphate pathway, which produces NADPH
