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Interestingly, the differential metabolites were mainly enriched in multiple vitamin and amino acid metabolism pathways, with the strongest enrichment identified for tryptophan metabolism ( p = 0.0006), retinol metabolism ( p = 0.009), cysteine and methionine metabolism ( p = 0.008), and vitamin digestion and absorption ( p = 0.01

Additionally, the significant weakening of the NRF2/SLC7A11/GPX4 antioxidant pathway results in ferroptosis of DA neurons in the SN (Fig

Kalava A, Midha M, Kurnatala LN, SchianodiCola J, Yarmush JM, How clean are the overhead lights in operation rooms

The minimum information reporting in bionano-experimental literature (MIRIBEL) standard should be followed for accelerating their clinical translation [312]