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Size restrictions for these junctions between the epithelial cells fluctuate but the high turnover of cells creates a window of increased permeability that can be leveraged by a translocating neurotherapeutic [22]

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Using hydrogen peroxide-induced senescent TM3 Leydig cells as an in vitro model, the study confirmed that FOXO4 maintains senescent Leydig cell viability and suppresses apoptosis