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Moreover, Lip-1 reduced microglial activation and the secretion of pro-inflammatory cytokines such as IL-6 and TNF-, while mitigating oxidative stress, lipid peroxidation, mitochondrial damage and neuronal injury following LPS exposure

Maintains mitochondrial function and reduces oxidative stress

Isoiquiritin apioside, an important component of Glycyrrhizae radix et rhizoma , could inhibit the upregulation of HIF-1 and HO-1 protein in lung tissue, downregulate the levels of PTGS2 and ACSL4, inhibit the ferroptosis in lung tissue of mice, and prevent intestinal I/ R-induced lung injury

In human embryonic stem cells, CHAC2 is highly enriched and is crucial for maintaining self-renewal capacity