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Description

This discipline reduces variability and makes published results more reproducible a recurring theme in peer review of peptide studies and a small but important contributor to data quality

Treatment with L-Carnitine (300 mg/kg) and alpha-lipoic acid (100 mg/kg) for 28-30 days in aged rats restores activities of succinate dehydrogenase, malate dehydrogenase, -ketoglutarate dehydrogenase, isocitrate dehydrogenase, and respiratory complexes I-IV to near-normal levels, indicating enhanced mitochondrial energy-producing capacity

Glutathione reductase activity determined from fresh samples compared with activity determined after storage at 20 C, (black symbols), 80 C (open symbols), or freeze-dried extracts of tissue (gray symbols) for ( a ) 1 week storage time or ( b,c ) 12 weeks storage time