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But let's be absolutely clear from the outset

While some studies address individual factors like diet, exercise, and smoking, there is a lack of comprehensive understanding of their combined impact, underlying mechanisms, and long-term consequences [32]

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For example, the StAR-related lipid transfer protein 3 ( STARD3) gene overexpression is evident in a variety of breast carcinomas [95] and especially in connection to HER2 amplification [96], exhibiting decreased adhesiveness of breast cancer cells as well as increased metastasis, and poor patient prognosis