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doi: 10.1016/j.psyneuen.2012.09.019 49 DiviccaroS.GiattiS.CioffiL.FalvoE.PiazzaR.CarusoD.et al

Although direct reports measuring fecal calprotectin after Spirulina plantensis supplementation are scarce, the significant reduction observed in the present study appears biologically plausible

These metabolite molecules then pass through phase II detoxification to become even more hydrophilic (water-loving) so that they can easily be eliminated