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Oxidative modifications of synovial proteins contribute to the formation of neo-antigens, triggering autoimmune responses [145]

All these carbon-based NPs have high surface area, high mechanical strength, and the ability to penetrate cell membranes, which hold a promising potential for treating PD

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Leptin interferes with the insulin signaling pathway, leading to impaired glucose and lipid metabolism, and promotes liver fat accumulation, which is characteristic of MASLD [213, 214]