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Wiest R, Lawson M, Geuking M

Physicians India 54 , 775782 (2006)

NicolasGChauvetCViatteLDananJLBigardXDevauxIet alThe gene encoding the iron regulatory peptide hepcidin is regulated by anemia, hypoxia, and inflammation

These findings suggest that after the loss of dopaminergic neurons, a vicious cycle of decreased dopamine releaseDRD2 signaling deficiencydecreased GSH synthesisoxidative stressdopaminergic neuron death will occur, leading to GSH deficiency and the progression of PD