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Description

At concentrations of 0.050.15 mg/mL, TH inhibited CuSO 4 -induced immune cell migration, suppressed NF-B and p38 MAPK signaling, reduced the expression of TNF- , IL-1 , and IL-8 , while enhancing secretion of the anti-inflammatory cytokine IL-10 (Li JJ

The knockout embryos undergo implantation and gastrulation but die before embryonic day (E)10.5, demonstrating the fundamental role of Tfam in mitochondrial biogenesis and embryonic development [50]