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Asparagine activates mTORC1 and contributes to the biosynthesis of purines and pyrimidines, as well as to the exchange of extracellular amino acids such as histidine, aspartate, and serine 37

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Normally, BECN1 interacts with the vacuolar protein sorting complex (Vps34) (Angelopoulou et al., 2018)

Model and physiological GSSR substrates are, for example, l-cysteine-glutathione disulfide (GSSCys) 9,10,11,12,13,14,15 , coenzyme A-glutathione disulfide 3,16 , as well as S -glutathionylated serum albumin 9,11,17,18,19,20 , sirtuin 21 , sulfiredoxin 22 , and peroxiredoxins 23,24,25,26,27,28,29