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Using them may also cause health concerns, and theyre currently only approved to treat a handful of specific medical conditions

J Biol Chem (2019) 294:1887380

The ANLS hypothesis draws heavily on data from techniques that measure metabolites and oxygen directly in the brain parenchyma (e.g., microsensors, microdialysis), emphasizing the rapid dynamics of a local lactate and oxygen pool (Hu and Wilson, 1997