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Why a neuromaturational model of memory fails: exuberant learning in early infancy

doi:10.1080/13697137.2019.1711051

Methods: Using the UNOS database, a retrospective cohort was extracted of recipients of first liver transplant with renal dysfunction (estimated GFR 2 mg/dL) and the impact of pre-LT MELD, pre-LT renal disease (acute kidney injury [AKI] or chronic kidney disease [CKD]), liver disease etiology (MASH vs alcohol-related liver disease [ALD] and other non-MASH), and 1-year trough tacrolimus (Tac) level on developing renal dysfunction following LT

Moreover, a reactive quinone methide metabolite of dauricine was observed and identified in MLMs, which spontaneously captured by GSH (Figure 4), and its GSH adducts can be suppressed by CYP3A inhibitor ketoconazole (Xie et al., 2016)