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After this first round of reactions, the two carbon shortened Acyl-CoA is recycled through subsequent rounds of -oxidation reactions generating Acetyl-CoA that enters the TCA cycle allowing the ATP synthesis by the oxidative phosphorylation (Figure 1)

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1, 2020 NLS Tang, J Hui Department of Chemical Pathology, and Li Ka Shing Institute of Health Sciences, Faculty of Medicine, The Chinese University of Hong Kong, Hong Kong SAR, China NLS Tang () MBChB, MD, FRCPA Metabolic Medicine, Department of Paediatrics and Adolescent Medicine, Hong Kong Children's Hospital, 1 Shing Cheong Road, Kowloon Bay, Kowloon, Hong Kong SAR, China J Hui () MBBS, FRCP(Edin), FHKCPaed Correspondence to: Prof

Lactobacillus Plantarum ZDY04 can significantly reduce the content of TMAO in serum and TMA in the cecum by regulating the structure of gut microbiota community, and effectively inhibit the development of atherosclerosis in mice (Qiu et al., 2018)