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The model suggests that this decrease is caused by the sequestration of Keap1 in the complex with Nrf2 due to its interaction with DEM

Myo-Ins potentiates IP3-evoked Ca responses and increases intracellular Ca store content in normal dermal fibroblasts Based on these findings, we next performed single-cell calcium imaging to determine whether intracellular Ca stores contribute to the enhanced ATP response observed in Myo-Instreated fibroblasts (5 mM, 3.5 h) (Fig