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For instance, SFN inhibited the viability of about 70% of HepG2 cells after exposure for 48 h at 20 M, but no significant cytotoxicity was observed in cultured human hepatocytes when exposed to 50 M of SFN for 48 h (Zhang et al., 2020)

Although -carotene, retinol, and lutein supplements theoretically have beneficial health impacts, the studys authors found, in a review of the long-term consumption of these nutrients and cancer risk, that it may lead to an increased risk of lung cancer (Satia et al., 2009)

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Yang, D., Rosenberg, H.F., Chen, Q., Dyer, K.D., Kurosaka, K