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Feature · Product Review
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Description

While cGAS signals via stimulator of interferon genes (STING) to induce predominantly IFN I, TLRs signal via the adaptor protein myeloid differentiation primary response (MyD)88 and the transcription factor NF-B to activate the expression of IL-1, IL-6 and IL-18 and of AIM2, NLRP3 and other elements of the inflammasome

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Scavengers and site-directed mimetics Mitochondria-focused antioxidant strategies concentrate defenses where ROS are made

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55,57 These injured or profibrotic tubular cells recruit macrophages, lymphocytes, and fibroblasts, promoting tissue fibrosis and leading to irreversible kidney damage

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Biotin and due to their strong interaction (strept) avidin require severe elution conditions

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