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Consistent with oxidative stress, we observed upregulation of glutathione biosynthesis (GSR, GST), superoxide dismutases (SOD1/2), and thioredoxin (TXN) in senescent cells

Moreover, a ketogenic diet, characterized by lower carbohydrate intake and relatively increased consumption of fats and proteins, holds potential in rectifying metabolic and inflammatory imbalances related to psoriasis (102)

218 Conceptually, however, it is not clear, if studies evaluating the response to an evoked visceral stimulus can be used to predict the response to spontaneous visceral pain, since the neurophysiological mechanisms are likely to be different