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Blood pressure or heart rate regulation abnormalities some people with CFS, particularly adolescents, experience symptoms of orthostatic intolerance

Quercetin Quercetin is a biologically active flavonoid antioxidant that is widely distributed in plants, including oak trees, onions and tea

Based on the regulatory pathways established in various physiological and pathological conditions, we propose the following hypothesis: The lipid metabolism reprogramming that occurs in the tumor microenvironment of TC may similarly disrupt the methylation patterns of specific gene regions (such as the promoter regions of tumor suppressor genes) by interfering with the demethylation process mediated by TET proteins and the methylation process mediated by DNA methyltransferases (DNMTs)

Table 1 Patients clinical characteristics