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Emerging evidence indicates that SOX2 also plays an important role in maintaining MSC stemness and suppressing senescence

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Nat Rev Microbiol 15:5563 Bulik-Sullivan BK, Loh P-R, Finucane HK, Ripke S, Yang J, Schizophrenia Working Group of the Psychiatric Genomics Consortium, Patterson N, Daly MJ, Price AL, Neale BM (2015) LD Score regression distinguishes confounding from polygenicity in genome-wide association studies

Both enantiomers have been shown to have opposing effects on vascular tone [R-PZQ causes contraction (150) whereas S-PZQ causes relaxation (151)] and may play a role in optimizing blood flow through splanchnic beds where schistosomes reside, thus contributing to their displacement (57)