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Vaccine-induced respiratory mucosal immunity is vital for protection against SARS-CoV-1 in animal models [46], and greater numbers of total tissue-resident T cells in the lungs have been associated with protection from severe COVID-19 [47, 48]

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Numerous well-defined necrotizing granulomas consisting of epithelioid histiocytes, perimetric cuffing of lymphocytes and plasma cell aggregates, and a caseous necrotic mass at the center were observed