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The sustained-release drug delivery facilitated by microneedle systems can streamline drug administration, achieve therapeutic concentrations within a specified time frame, and minimize potential systemic toxicity [185]

Genetic polymorphisms in GST genesparticularly GSTM1 and GSTP1influence individual detoxification efficiency and may affect how the body processes medications and environmental stressors

Therefore, antioxidative therapy can be considered a new therapeutic strategy for the treatment of gliomas

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