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et al., 2019

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Guo Y, Jiang H, Wang M, Ma Y, Zhang J, Jing L (2023b) Metformin alleviates cerebral ischemia/reperfusion injury aggravated by hyperglycemia via regulating AMPK/ULK1/PINK1/Parkin pathway-mediated mitophagy and apoptosis

It is a cofactor for numerous enzymes (e.g., hydrolases, oxygenases, and dioxygenases) and is involved in many metabolic processes (e.g., synthesis of adrenaline from tyrosine)