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Water-soluble vitamins are vitamin C, the B vitamins and folic acid

Immunofluorescence staining Ovarian tissues and GCs were fixed with 4% paraformaldehyde and permeabilized with 0.1% Triton X-100, followed by incubation with the corresponding antibodies at 4 C overnight

In HD models, striatal Mn accumulation is diminished (including in HD patient-derived neural progenitors and HD mouse striatal cells) and has been linked to impaired XK/Rab11-dependent Mn handling and disrupted Mn-dependent ATMp53 signaling, with Mn sensitivity varying by lineage and developmental stage 264