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Patients randomized to pemetrexed also received folic acid and vitamin B 12

Nature 568 , 351356 (2019)

Once diagnosed, treatment options can include dietary adjustments, supplements, or even injections

Excessive neuronal iron promotes NFT formation via the activation of CDK5 (Cyclin-dependent kinase 5)/P25 complexes and GSK-3 (Glycogen synthase kinase-3 beta) kinase pathways