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These differing findings may be attributed to variations in lactation stages across studies, the extension of analyses over longer periods, increased sample numbers and sampling frequency, population- and mother-specific dietary differences (particularly mineral supplementation), and inconsistencies in sample collection protocols

125 Not only is the TSC1TSC2 complex maintained in its active form (phosphorylation of TSC1) by AMPK, but it is also activated by the REDD1 (regulated in development and DNA damage responses 1) protein, itself activated under hypoxic condition