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Visc Med 32(3):172177

The hydroxyl groups on the terminal rings can also form mono- or diester derivatives with fatty acids, which are the predominant forms in many natural sources and further contribute to the diversity of astaxanthin compounds observed in biological systems ( Substantial evidence indicates that AST can downregulate microglial activation and reduce the production of cytotoxic factors

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[62] Clarke subsequently administered chelation therapy to patients with angina pectoris and other occlusive vascular disease and published his findings in The American Journal of the Medical Sciences in December 1956