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Polymer conjugates as therapeutics: future trends, challenges and opportunities

The SCS is composed of a single layer of LECs interspersed with macrophages and dendritic cells that collect lymph, and this single-layer structure can impede lymph from entering the lymph node parenchyma and guide lymph to diffuse through the cortical sinuses [24, 25]

CD8+ T cells and lipid metabolism Lipid uptake in CD8+ T cells The tumor microenvironment is enriched with various types of lipids, which CD8+ T cells take up through different lipid transporters