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doi: 10.1002/hep.28964

Following endogenous growth hormone release, downstream production of insulin-like growth factor-1 (IGF-1) contributes to many of the physiological processes associated with growth hormone biology

Interestingly this enhancement of the glycolytic flux induced by NS5A does not result in the accumulation of glycogen suggesting a more complex rewiring of intracellular intermediate metabolites than expected in hepatocytes facing an increased glycolysis